Whenever a nontoken artifact creature you control deals combat damage to a player, that player gets two poison counters. (A player with ten or more poison counters loses the game.)
原文A player with ten or more poison counters loses the game. This is a state-based action and doesn’t use the stack. In other words, it happens immediately and players can’t respond to it, just like a player losing the game due to having 0 or less life.