Norman Osborn can't be blocked.
Whenever Norman Osborn deals combat damage to a player, he connives. (Draw a card, then discard a card. If you discarded a nonland card, put a +1/+1 counter on this creature.)
: Transform Norman Osborn. Activate only as a sorcery.

Indestructible
: Add .
, , Exile a creature you control: Harness The Soul Stone. (Once harnessed, its ∞ ability is active.)
∞ — At the beginning of your upkeep, return target creature card from your graveyard to the battlefield.

When Miles Morales enters, put a +1/+1 counter on each of up to two target creatures.
: Transform Miles Morales. Activate only as a sorcery.

When Gwen Stacy enters, exile the top card of your library. You may play that card for as long as you control this creature.
: Transform Gwen Stacy. Activate only as a sorcery.

When Peter Parker enters, create a 2/1 green Spider creature token with reach.
: Transform Peter Parker. Activate only as a sorcery.

When Eddie Brock enters, return target creature card with mana value 1 or less from your graveyard to the battlefield.
: Transform Eddie Brock. Activate only as a sorcery.

The "legend rule" doesn't apply to Spiders you control.
Whenever you cast a spell from anywhere other than your hand, you may copy it. If you do, you may choose new targets for the copy. If the copy is a permanent spell, it gains haste. Do this only once each turn.

Deathtouch, lifelink
Whenever Gwenom attacks, until end of turn you may look at the top card of your library any time and you may play cards from the top of your library. If you cast a spell this way, pay life equal to its mana value rather than pay its mana cost.

Flying, first strike, trample, lifelink, haste
At the beginning of combat on your turn, other Spiders you control gain flying, first strike, trample, lifelink, and haste until end of turn.

When Anti-Venom enters, if he was cast, return target creature card from your graveyard to the battlefield.
If damage would be dealt to Anti-Venom, prevent that damage and put that many +1/+1 counters on him.

Whenever a nontoken creature you control deals combat damage to a player, create a token that's a copy of it, except it isn't legendary.

Vigilance, lifelink
Darkforce Inversion — When Mister Negative enters, you may exchange life totals with target opponent. If you lose life this way, draw that many cards.

Return up to six target creature cards with different names from your graveyard to the battlefield.

Other Villains you control get +2/+2.
Your maximum hand size is eight.
At the beginning of your end step, if you have fewer than eight cards in hand, draw cards equal to the difference.

Convoke (Your creatures can help cast this spell. Each creature you tap while casting this spell pays for or one mana of that creature's color.)
At the beginning of combat on your turn, look at the top five cards of your library. You may put a creature card from among them onto the battlefield. Put the rest on the bottom of your library in a random order.